In Ethiopia, snap bean is an important vegetable crop with high nutritional value, which is grown as a cash crop by large and small scale farmers for local and export markets. However, the yield of the crop is constrained by a number of factors including lack of improved varieties, poor soil fertility and inappropriate Rhizobium inoculation. Therefore, a field experiment was conducted to identify suitable varieties and Rhizobium strains for growth and productivity improvement of snap bean at Woramit research site of Amhara Agricultural Research Institute (ARARI) from February to May in 2023. The experiment consisted of 4 (four) varieties (Plati, BC 4.4, Ampere, and Pop Varend Seed) and 2 (two) Rhizobium strains (EALHB- 429 and HBA15) including the control laid out in 4x3 factorial arrangements in RCBD with three replications. The phenological, growth, and yield related parameters were collected and analyzed using R software (version 4.1.3). The analysis of variance showed that variety and Rhizobium inoculation significantly influenced most of the tested parameters of snap bean. Plati and BC 4.4 varieties performed well in most of the tested parameters of snap bean, such as number of pods per plan1 , pod length and pod diameter, marketable green pod yield, and total green pod yield, compared to other tested varieties. Inoculation of plants with HBA-15 and EALHB-429 strains increased the growth and yield parameters of snap bean. HBA-15 (9.52 t ha-1 ) and EALHB-429 (8.84 t ha-1 ) Rhizobium strains increased the total green pod yield by 79% and 66%, respectively, compared to the control (without Rhizobium inoculation) treatment. Nodulation had a strong and positive relationship with the marketable and total green pod yield of snap bean. Interaction effect of Rhizobium inoculation and varieties interact to influence leaf area index, number of nodules plant-1 , number of pods plant-1 and effective nodules. Therefore, it is concluded that Plati and BC 4.4 varieties and HBA-15 and EALHB429 Rhizobium strains, are considered a promising technologies to enhance the production of snap bean in Bahir Dar Zuria district and areas with similar agro-ecology. As the study was conducted in a single location and season, it is also recommend repeating the experiment in multi-location and seasons.