This study looked at how perceived organizational politics affected workers' job satisfaction at Bahir Dar University. The study used a quantitative research strategy that was explanatory in nature and adhered to a postpositivist research ethic. Data were gathered via a survey of 380 (out of 7684 total populations) randomly selected academic and administrative staff members of the university utilizing a standardized questionnaire in order to meet the research objectives. Results from the multiple linear regressions and descriptive statistics generally indicated that at Bahir Dar University, employees' perceptions of organizational politics have a significant impact on their job satisfaction. 76% of employees' job satisfaction was explained by the three dimensions of perceived organizational politics. According to the findings of this study, all aspects of perceived organizational politics, including general political behavior, go along to get ahead, and pay and promotion practices, negatively affect employees' job satisfaction in a statistically significant way. Finally, the researcher suggested that the university design strong and effective communication and relationship programs that can ease potential tension in employee-to-employee and employee-to-management relationships in order to improve such undesirable perceptions among their employees.