Background: The term diabetes mellitus describes a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia with disturbance of carbohydrates, fats and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Objective: “assessment and factors associated with knowledge among patient with type 2 diabetic mellitus for choosing the right food in yekatit 12 hospital, Addis Ababa, Ethiopia, 2022. Methods: a simple random sampling method was applied to select the study participants. Data were collected using an interviewer administered pretested structured questionnaire. Data were analyzed using SPSS version 20.Descriptive statistics was used to describe the socio-demographic variables.Bi-variate analyses was done to see the association between eachindependentvariables and the outcome variables. Multivariable analysis was carried out to identify independent predictors of the dependent variable. Odds ratio along with 95% CI were used to measure the strength of the association between variables of interest. For all statistical significance, the cut- off value was P < 0.05. Result: about 47.3% ofrespondents had good knowledge, towards choosing the right food.In multivariable analysis being male [AOR=0.51, 95%CI: (0.31, 0.84)] was negatively associated with knowledge of type 2 DM patients for choosing the right food.Conclusion: About 47.3% of the type 2 diabetic patients had good knowledge towards choosing the right food. Being male was negatively associated with knowledge of type 2 DM patients for choosing the right food. Recommendation: Hospital based intervention program should be implemented to improve knowledgeespecially for male patients. Keywords: Type2 diabetes, knowledgeand factorsfor choosing the right food.