Accesses to safe water is a universal need however, many of the world’s population lack access to adequate and safe water. Consumption of water contaminated causes health risk to the public. A convenience/purposely sampling technique and laboratory based comparative study conducted on municipal drinking tap water quality from August up to April 2017/18 at selected slum areas of Addis Ababa, to isolate indicator microorganism of water quality and to analyze the physiochemical parameters of water samples. A total of 27 tap water samples collected from nine villages that is Addis Ketema sub city: awetobistera, gojamberenda and minaleshtera. Arada sub city: piasaserategnasefere, datsonsefer and gedamsefere, and Kirkose sub city: cherqosesefere, kera and gotera. & transported to Addis Ababa water and sewerage authority and Ethiopian public health institute laboratory for bacteriological and physicochemical analysis respectively.Out of 27 water samples from municipal drinking water sources, 5(18.5%) samples were found positive or presence for total coliform (the probability of contamination by waste water) and absence for thermo tolerant coliform or E.coli whereas the remaining 22(81.5%) had no total coliforms. Analysis of physicochemical parameters revealed turbidity at of the 27 water sample 18(67.7%) had greater than the standard (this might be due to leaked pipes)while the remaining 9(33.3%) had a turbidity of less than 5 NTU. 27(100%) of the sample had pH range 6.5-8.5. Analysis of total dissolved solids (TDS) showed that 27(100%) of water samples had TDS less than 1000 (mg/l).Strict inspection of the pipe lines along the distribution system and replacement of leaked pipes and shallow pipes deepen can solve incompliance of turbidity and residual chlorine parameters and giving information’s for Communities living in the slum areas about home drinking water treatment mechanisms (disinfection methods).