ABSTRACT Pepper root rot which is caused by the pathogen Phytophthora capsici is among the most important disease challenging hot pepper production. The objectives of the study were to assess the prevalence and incidence of pepper root rot disease at four Kebele Administrations (KAs) and to evaluate the combine effect of planting bed preparation and fungicides against pepper root rot disease at Dera district in South Gondar administrative zone. The field assessment was conducted during the main cropping season of 2017 and totally 40 farmer fields at four KAs were assessed. Disease prevalence, incidence and field management practices were recorded in each farmer field. Most of the farmers (70%) respond that the main constraint of their hot pepper production were root rot disease. Hot pepper disease can be managed by cultural practices; however no one farmer followed the recommended cultural management practices. Out of 40 pepper field assessed for presence of disease 19(47.5%) were infected by different diseases. The hot pepper disease prevalence was ranged (40%-60%) across Kebeles. Laboratory finding revealed that diseases found infecting hot peppers in the inspected area and field experiment were Phytophthora capsici (53%), bacterial blight (Pseudomonas solanacearum ) (27%) and fusarium wilt (Fusarium oxysporum)(20%). Among the hot pepper field surveyed mean higher incidence were recorded in Jigna kebele 56.50% and the minimum of 38% at Zara kebele. Field experiment showed fungicides (ridomil) combined with raised bed treatments had statistically lower (14.80±6.51) mean AUDPC values than those applied at flatbed with-out fungicide (59.2 ±1). The finding also revealed that the applied combined treatments (Raised bed + Ridomil) significantly reduced root rot incidence (13.33%) compared with flatbed without fungicide the control (53.33%). Significantly highest height of plant, fruit number per plant and yield were recorded on fungicide and raised bed treated pepper bed than control (flatbed without fungicide). Yield loss protected percent due to combine of raised bed preparation and ridomil use were reach up to 44.7%.. xv Partial budget analysis showed that raised bed with ridomil fungicide application on pepper production have highest net return rate than others followed apron star with raised bed treated pepper production. As conclusion the experimental finding showed that raised bed preparation combined with ridomil indicated the best in management of pepper root rot disease. Hence to boost hot pepper production in pepper root rot area should be controlled by using combined of cultural method (raised bed and ridge bed) and Ridomil application. However further studying on the farmer’s field is required. Key words: Bed preparation, fungicide, pepper, Phytophthora capsici, root rot