The purpose of this study was to examine the effect of continuous, interval, and combined training methods on distance running performance in the Ethiopian Hotel Athletics Club. To this end, a total of thirty (N=30) participants were selected from the Ethiopian Hotel Athletics Club as subjects. This study employed a quantitative research approach with a quasi-experimental design. Specifically, to achieve this objective, thirty athletes from the Ethiopian Hotel Athletics Club were divided into three equal groups: continuous, interval, and combined. Following this, a 12-week training program was implemented, and pre- and post-test assessments were conducted. Both descriptive and inferential statistics, including paired sample t-tests, one-way ANOVA, and MANOVA, were used to analyze the data. SPSS software was employed to determine significant differences between the training methods and their impact on athletic performance. The results revealed that all groups showed improvements in performance after the 12-week training program. However, the interval and combined training groups demonstrated greater gains in VO2 max, strength endurance, and speed compared to the continuous training group. Notably, the interval group experienced the largest increase in VO2 max. MANOVA analysis revealed significant differences between training methods in post-test VO2 max and speed, with moderate effects on these performance measures. Although there were no significant between-group differences in strength endurance or the 2.4km run test, overall performance improvements were evident across all groups. Furthermore, Box's test for equality of covariance matrices and Levene's test for error variance confirmed homogeneity of variances and equal variances in the dependent variables, respectively. Subsequently, these findings suggest that the results are reliable and not influenced by unequal variances. Finally, interval and combined training methods are more effective for improving aerobic capacity and speed compared to continuous training. Although all training methods showed limited effects on strength endurance, further research with larger sample sizes is needed to validate these findings and explore the potential benefits of strength training for distance runners.