The ongoing conflict in the Amhara region of Ethiopia poses a critical threat to social, economic, political, and human well-being. This study investigates the impact of the conflict on the livelihoods of communities in Mecha Woreda and their coping strategies. A mixed-methods research design with a convergent parallel approach was employed to assess the impact of the conflict on agricultural production, social cohesion, and access to agricultural inputs and outputs. A total of 392 respondents were selected through simple random sampling from two kebeles, Enguti and Kudmi, to obtain quantitative data. Additionally, 10 participants were purposively chosen from within the sample for in-depth interviews to capture rich qualitative insights. Data were collected using two key instruments: a structured questionnaire and in-depth interviews. The questionnaire gathered data on agricultural practices, food security, income changes, and coping responses, while the interviews explored lived experiences, perceptions, and adaptive strategies in greater depth. The findings reveal substantial disruptions to agricultural activities, land abandonment, and sharp declines in crop yields, leading to widespread food insecurity and economic hardship. The conflict has also eroded traditional social networks and community bonds while restricting access to markets and essential inputs. In response, communities have resorted to coping mechanisms such as reducing food intake, selling livestock, seeking alternative income sources, and turning to religious practices for psychological support. This study contributes to a deeper understanding of how conflict destabilizes rural livelihoods and offers insights for development planners and policymakers working in similar conflict-affected contexts.