Many Reinforced Concrete (RC) buildings are damaged by Terrorist attacks all over the world. It results in damages to assets, loss of life, and social panic. In principle, structural designs ensure the protection and safety of occupants and the integrity of the structure itself. However, in reality, this is not upheld when a structure is struck by extreme blast loading. There are limited previous studies that conducted the combined effect of blast and impact load on RC beam-column joints and the application of Carbon Fiber Reinforced Polymer (CFRP) strengthening mechanisms to increase the reduced load resistance capacity. The main aim of this study is to investigate the combined effect of blast and impact load on RC beam-column joints and the use of CFRP strengthening mechanisms. The explicit dynamic analysis software LS-DYNA 2022 is used to establish numerical investigations. The experimental results from the literature were used to validate the finite element analysis LS-DYNA explicit dynamic analysis software. The parametric studies were conducted with a variation of blast load stand-off distance, blast weight, blast load incident angle, weight of impact, impact load stand-off distances, and CFRP strengthening methods. The finite element investigation result shows that The blast load stand-off distance and blast weight variation have a considerable effect on displacement responses of RC beam-column joints under the combined effect of blast and impact loads. The maximum deflection is observed at 90⸰ blast load incident angle for both 5 kg and 50 kg blast weight at 2m SD of blast load. The 1 layer at 90 CFRP orientation is the best strengthening layout of RC Beam-column joint under the combined effect of blast and impact loads without debonding failure. Keywords: RC Beam-column joint, Impact–blast combined load, LS-DYNA, CFRP.