Introduction, In Ethiopia, there is no scientific evidence indicating the anthropometric characteristics, nutritional intake and physical fitness performances of men premier league volleyball players. Thus, the purpose of the study to investigate the relationship between anthropometric characteristics, nutritional intake status and physical fitness quality of men volleyball player’s in Ethiopian premier league. Methods To achieve set goal of the present study adapted a cross-sectional survey and correlational research designs. 48 men volleyball players encompassed from four Premier League clubs who are actively participate in the 2021/22 competition year. MC (n=12), WD (n=12), TBD (n=12), and ETDF (n=12). To obtain necessary data practical field test and self-reporting diary were used as data collection instruments. In the study twenty anthropometric, three macronutrient and three physical fitness variables were assessed. Descriptive statistics, Onesample T-test, Pearson Product Moment correlation coefficients, Multiple Regressions were employed by using SPSS (V.25). Result, the finding of this study revealed that the average height, weight, spike and blocking reach of Ethiopian men volleyball players was 1.88 (±.093) cm, 76.31 (±8.29) kg, 309 (±18.56) cm and 299.1 (±18.64) cm, which was significantly different and lesser than to the international players p<0.01. In the other finding, energy, carbohydrate, fat, and protein intakes of volleyball players expressed in units per kilogram of body weight which was 30.30 (±2.68)kcal, 3.71 ±(.30)g, 1.10 (±.12)g and 1.38 (±.16)g, which was significantly different and lower than to the recommended guidelines p<0.01. Also, other descriptive result, the mean sprinting (speed), medicine ball throw(strength) and vertical jumping (power) score of Ethiopian men volleyball players was 1.58 (±12.55)sec, 6.44 (±.77)m, 59.06 (±13.31)cm. In correlation finding, most of the anthropometric variables positively correlated with selected physical fitness components, in other independent variable carbohydrate nutrient only have positive correlation with whole selected physical fitness trait. In regression model result shows, upper leg length and body mass index found to be most predictor of speed quality; weight and sitting height found to be the most predictor of upper body strength and spike reach height and standing reach height for explosive power capacity, also in the other variable finding carbohydrate was most predictor of speed and strength quality of payers.