Background; Pin site infection after treatment with EX FIX complicates significant proportion of cases. Studies show varying rates of occurrence of pin site infection the associated treatments, functional disability, prolonged pain, and lost wages can lead to substantial psychosocial impairment, economic burden to the patient, and stress on the health care system. A number of potential factors have been identified to increase rate of pin site infection, including old age, male gender, tobacco smoking, diabetes, high-energy fracture and time of intervention Methods and materials; The study will be conducted using a retrospective cross-sectional study in patients who were admitted and operated with external fixation who fulfill the inclusion criteria and were on follow up in TGSH orthopedics department referral clinic from September 1,2020 to September 30/2023. Patients with external fixation will be reviewed and patients with pin site infection will be analyzed in particular. Simple binary variable regression analysis will be used to analyze the association between variables. The data will be analyzed using SPSS software and the results will be presented in tables and pie chart. Result; A total of 170 of 179 patients (94.9%) were included: 161 males and 10 females with the Average age of 32.89 +-13.168 years. The estimated prevalence of PSI was 44.4% Results of Binary logistic regression showed that timing of starting antibiotics from injury (AOR =2.064; 95%CI 1.007 – 3.996) and Time of surgery done from injury (AOR = 3.839; 95% CI 2.007 – 7.342) was significantly associated with PTI. Conclusion; The overall prevalence of PTI is comparable with study done in Sulaimani Hospitals in Iraq (1). The independent risk factors for PTI were time surgery from time of injury and delayed use of prophylactic antibiotics from time of injury