Background: Delay in healthcare-seeking is defined as seeking care in a health facility to a child after 24 hours of the onset of illness or functional limitations. A large number of under-five children died due to dehydration as a result of not timely receiving proper health care services for diarrhea diseases. In this regard, there was little evidence on factors associated with delay in health care seeking for diarrheal diseases and the lived experiences of caregivers for these public health issues in the study area. Objective: To assess delays in healthcare seeking for diarrheal disease and its associated factors among caregivers with under-five children in health centers, Bahir Dar city administration, Northwest Ethiopia, 2022. Method and Materials: An institution-based cross-sectional study with a mixed approach was conducted from 05 May to 05 June 2022. A phenomenological approach was used for the qualitative data part. Quantitative data was collected from 374 participants using a structured interviewer-administered questionnaire and chart review. The study participants were selected by using a systematic random sampling technique. The data were analyzed using a statistical package for social science software version 25. Qualitative data was collected from five participants via in-depth interviews and analyzed using open code software. Bi-variable and multi-variable logistic regression models were used to identify associated factors. Variables with p-value < 0.05 in multivariable analysis were considered as statistical significance. The qualitative data were transcribed, translated, coded, thematized and interpreted accordingly. Results: In this study, the prevalence of delay in health care seeking for diarrheal diseases was 53.48%. Large family size (AOR=2.64,95%CI:1.26-5.4), poor knowledge about diarrhea danger signs (AOR = 3.25,95%CI:1.6-6.6), difficult to pay for treatment costs (AOR = 2.95,95%CI:1.6- 5.3), caregivers who did not visit health facilities as the first response to diarrhea (AOR = 3.94, 95%CI:1.96–7.9), when the presenting symptom was only diarrhea, (AOR = 2.39,95%CI:1.01- 5.63) and no information about the importance of early healthcare-seeking (AOR= 4.88,95%CI: 1.91-12.43) were determinants of delay. awareness, barriers, compliance and perception were emerged themes. Conclusion: The prevalence of delay in seeking healthcare for children with diarrhea was high. large family size, poor knowledge about diarrhea danger signs, difficulty to pay for treatment costs, etc, were factors associated with delay health care seeking. Keywords, Diarrhea, Delay in care seeking for diarrhea, Under-five Children, Ethiopia