Background: Time is a precious commodity and wasting it is unprofitable. In the health profession, time management is of utmost importance since time spent by health professionals is time not spent with patients, and this affects the quality of treatment provided to patients. However, time management practices and associated factors among health professionals were not well studied or documentedin the study area. Objective: This study aimed to assess time management practices and associated factors among health professionals working at public hospitals in Bahir Dar city, 2022. Methods: An institution-based cross-sectional study supplemented with a qualitative study was conducted from April 21 to May 20, 2022,among health professionals working in public hospitals. A simple random sampling technique was used to select 416 study participants. A pretested self-administered questionnaire was used to collect quantitative data, and an interviewer guide was used to collect qualitative data to complement quantitative data. Purposive sampling was used in the qualitative study, and 6 in-depth interviews were carried out till saturation was reached. The quantitative data were entered into Epi Data version 4.0 and analyzed using SPSS 25.0 whereas the qualitative data were analyzed manually using thematic analysis. To identify the associated factors, bi-variable and multivariable logistic regression analyses were used. The degree of associations was interpreted using odds ratio and 95% confidence interval at <0.05 p-value. Results:From 416 proposed participants, 410 were involved yielding a 98.5% response rate. The magnitude of time management practice among health professionals was 66.1% (95% CI: 61.5%-70%). Age ranges 25-29 (AOR = 3.961, 95% CI: 1.068, 14.682) and 30-34 (AOR = 6.240, 95% CI: 1.640, 23.749), planning (AOR = 6.032, 95% CI: 3.478, 10.463), compensation and benefitpackages (AOR = 1.888, 95% CI: 1.077, 3.309), responsible to work (AOR = 2.119, 95% CI: 1.192, 3.768), time waster (AOR = 1.855, 95% CI: 1.058, 3.251) and staff shortage (AOR = 0.535, 95% CI: 0.319,0.896) were the significant factors with time management practice. Conclusion and recommendations:As compared to other studies conducted in Ethiopia, this study found modest degree of time management practice among health professionals. A hospital could improve its time management practices by providing training on planning, being a low time-waster and highly responsible at work, and designing compensation and benefits packages. Keywords:Time Management, Factors, Health professionals, Public Hospitals, Bahir Dar