Background: Globally, adults consume an excess salt with an average of 10 grams of salt per day. In Ethiopia 96.2% of adults consume more than recommended (5 grams) daily salt intake which is estimated to 8.3 grams. It is responsible for more than 3 million deaths from heart disease, stroke, and related causes each year. Eighty percent of these deaths occur in low- and middle-income countries. Surveillance of salt reduction strategies such as measuring and tracking population salt intake sources of salt, knowledge, attitude, practice toward salt, and salt level in foods are an essential part of any intervention. Objective: To assess the salt intake reduction practice and associated factors among adults in Bahir Dar city, Amhara Region, Ethiopia April, 2022. Methods: We conducted community based cross-sectional study among 634 adults in Bahir Dar City on April, 2022. We used a stratified multistage sampling techniques to recruit study units. Structured questionnaire was used for data collection using Kobo Collect version 2022.1.2 and Statistical Package for Social Science version 25 was used for analysis. Tables, frequency, percentage, mean and standard deviation were used for descriptive analysis. Variables of p-value <0.25 during bi-variable logistic regression analysis were considered for multivariable logistic regression analysis. Finally, variables with p-value <0.05 along with a 95% confidence interval (CI) not included one were used to declared statistically significant variables. The assumptions of logistic regression analysis were assessed using the Hosmer-Lemeshow model fitness test. Results: A total 618 adults were participated with a response rate of 97.5%. Among the participant, 450 (72.82%) had poor salt intake reduction practice. Males [AOR=2.20, 95% CI (1.39-4.06)], urban residents [AOR=2.59, 95% CI (1.72-3.92)], not received advice to reduce salt [AOR=1.94, 95% CI (1.25-3.00)], not know the daily recommended salt intake per person [AOR=4.73, 95% CI (1.94-11.52)], and believing reducing salt for own health is less important [AOR=2.68, 95% CI (1.29-5.58)] were significantly associated with poor salt intake reduction practice. Conclusion: An estimated three fourth of adults in Bahir Dar city had poor salt intake reduction practice. Males, urban kebele residents, not received advice to reduce salt, do not know the daily recommended salt intake per person and believing reducing salt for own health is less important were a significant associated variables with poor salt intake reduction practice. Key words: salt intake, reduction practice, adult, Bahir Dar, Ethiopia