The construction of different infrastructures like buildings, bridges, roadways, and railways is increasing from time to time in the construction industry. To fulfill this construction demand, a large amount of concrete is required. Concrete is a mixture of cement, sand, coarse aggregate, water, and different additives. In this study, the capability of Metakaolin as a partial substitute for cement in C-25 concrete production with 0%, 10%, 20%, and 30% replacement of Ordinary Portland Cement (OPC) by Metakaolin (MK) with 0.49 percent water to cement ratio is investigated. The study examines; the chemical properties of MK, Physical properties of cement paste, workability, compressive strength, water absorption, density, sulfate attack, and microstructure by Fourier transformed infrared spectroscopy (FTIR) and Thermogravimetric analysis (TGA) of concrete. The chemical composition of Metakaolin was examined and the summation of SiO2, AlO3, and FeO3 is 93.9% and the ash was classified as class N Pozzolan. The normal consistency percent of water increased from 27% to 35 as the Metakaolin replacement amount increased from MK0% to MK30% and both initial and final setting time rang increased as the MK replacement amount increased. the workability of Metakaolin concrete become decreases by 30mm-20mm with Metakaolin content increase from MK0% to MK30%, Concrete containing 10% of MK replacement shows better compressive strength it increases by 0.43%, 1.27%, 3.14%, and 4.24% at 3 rd ,7 th ,28 th and 56 th day respectively, with the conventional concrete but the density, sulfate attack decrease with an increase of the Metakaolin content. Kay Words: -Physical Properties, Compressive Strength, Metakaolin, FTIR, TGA,