Background: - Diabetes mellitus is a serious threat to global health that respects neither socioeconomic status nor national boundaries. Recently social challenges of diabetic patients are a public health problem and an important area of research. The main purpose of this study was to explore the social life challenges of diabetic patients who have a follow-up in Bahir Dar City Administration Public Health Facilities, North West, Ethiopia in 2021. Methods: - A Facility-based cross-sectional convergent parallel mixed study design was conducted, and to the qualitative data phenomenology approach was used. Data were obtained from 412 participants using an interviewer-administered structured questionnaire and focus group discussion. The respondents were selected by using a systematic random sampling method. The data were entered into Epi data version 4.6 and exported to Statistical Package for Social Sciences version 23. The quantitative data were analyzed through different descriptive measures and binary logistic regression, then after thematic analyses the qualitative data collected through focused group discussion were triangulated with the quantitative data. Result: - The overall magnitude of social life challenges of diabetic patients to the study variables was 62.8% at [61.56,64.4]. It was related to discrimination from social events, absence of family and social support, the difficulty of following dietary recommendation and giving birth, and diabetic mellitus affecting their job and carrier were above the mean score. Using multivariate logistic regression, the relationship and the strengths between an outcome variable and explanatory variable, showed that there is a statistically significant relationship between integration of health services (AOR,3.473(1.62,7.444)), cardiovascular disease (AOR,2.888(1.603,5.2) foot ulcer (AOR,4.764(1.159,19.581), education (AOR,2.44(1.022,5.827) ,family size (AOR,3.654 (1.253, 10.656), and depression (AOR,5.315(1.989,14.202) to the social life challenge of diabetic patients at (p<0.05, confidence interval, 95%). Conclusion and recommendation: - Overall magnitude of social life challenges of diabetic patient were high in Bahir Dar. it was significantly related to education, family size health service integration, cardiovascular disease, foot ulcer, and depression. This study suggests that health facilities service improvement and investigating other factors that challenge the life of diabetic patient is crucial. Key words; - Diabetes, magnitude, social life challenge, social related factor