Shallot (Allium ascalonium L.) is one of the most important cash crops in Ethiopia. The quality and yield of bulb shallot under farmer’s condition is low because of lack of proper soil fertility management practices, lack of proper knowledge on optimum amount of nitrogen and farm yard manure fertilizer application and poor agronomic practices. Therefore this study was initiated to assess the response of true seed shallot to nitrogen and farmyard manure application rate on its growth and yield. The current study was conducted at Debre Markos, Northeast Ethiopia, during 2020/2021croping condition. The study consisted four levels of nitrogen (0, 100, 150 and 200kg ha -1 ) and five levels of farmyard manure (0, 5, 10, 15 and 20ton ha -1 ). The experiment was laid out in 4x5 factorial combinations in Randomized Complete Block Design (RCBD) with three replications. Data was collected on growth and yield parameters of central selected plants and analyzed using SAS software. The analysis of variance revealed that significant variation was observed from fertilizers tested on plant height, leaf length, leaf number, bulb neck diameter, bulb diameter, bulb weight, total bulb yield, marketable yield, and unmarketable yield. The highest plant height (71.23cm) was obtained from combined application of 200kg ha -1 nitrogen with 20ton ha -1 farmyard manure whereas the shortest plant height was recorded from the control. The highest total bulb yield (32.19tha -1 ) and (32.12tha -1 ) was obtained from combined application of 200kg ha nitrogen with 20ton ha -1 farmyard manure and 150kg ha -1 with 15ton ha -1 farmyard manure. Combined application of 200kg ha −1 nitrogen with 20ton ha −1 farmyard manure gave slightly higher total bulb yield of shallot and 150 kgha −1 nitrogen with 15ton ha −1 farmyard manure although statistically on par. The partial budget analysis suggests that using combination of 150kg ha -1 nitrogen with 20ton ha -1 farmyard manure shallot would give better yield. Therefore, it is suggested as a further line of work in the study area and other areas having similar agro ecological condition.