Hybrid two or more fiber-reinforced composites are generally prepared to enhance different properties as compared to single-fiber reinforced composites. The aim of the current study was to investigate the mechanical properties of hybrid sheep wool and sisal fiber reinforced epoxy composites. Sheep wool and sisal fibers are natural fibers that can be obtained from sheep and sisal leaves respectively. After extracted and treated their fibers, the woven yarn fiber mat was prepared. Then woven hybrid composite was fabricated with a 20% weight fraction of fiber by using hand layup fabrication techniques. Composites samples were prepared under five different weight percentage ratios of sheep wool to sisal fiber 0:20, 5:15, 10:10, 15:5, and 20:0. And each weight percentage of a sample was fabricated with two different angles (0-90° and ±45°) of orientations.Their mechanical properties were examined by varying angles of orientation and fiber content of composite .Specimen preparation and testing were carried out as per ASTM standards. For mechanical properties characterization, tensile strength, compressive strength, flexural strength, and impact strength tests were conducted. From the experimental test results, it was observed that the tensile, compressive, flexural strengths increase directly with increase sisal fiber weight percentage of composite samples in both 0-90° and ±45°angle of orientations. However, between the two angles of orientation, the tensile and flexural strengths of the hybrid sheep wool and sisal fiber epoxy composite samples were highest in 0-90°angle orientations composite samples. On other hand, the compressive and impact strengths were highest in ±45°angle orientation of the composite samples. Generally, from all composite samples in both ( 0-90° and ±45°) angles of orientations, composite sample four (SA4 and SB4) were better tensile, compressive, flexural, and impact strengths. The experimental test result shows that, the hybrid sheep wool, and sisal fiber epoxy composite are alternative materials for the interior part of automotive applications like and interior roof and door panels. Keywords: Sheep wool fiber, Sisal fiber, Epoxy, Composite, Mechanical properties, Hand layup