This study examined the fish marketing chain and livelihood of local fishers at Lake Tana. The southern Gulf of Lake Tana has three major landing sites (Saint Michael, Saint George and Robit Bata). The study areas were selected purposively as the fish market outlet of Lake Tana is confined to the southern part of the Lake near Bahir Dar city. Primary data were generated from 90 fishers respondents selected randomly from the three landing sites. In addition, market related data were collected from 5 assemblers, 6 retailers, 2 wholesalers, 30 consumers and 19 hotels. Both descriptive and econometric analyses were used to analyze the data. From sample motorized and reed boat owner fishers were 33.3% and 66. 7%, respectively. Fishing, crop production, animal husbandry, petty trade and causal laborer contributed 66%, 21 %, 6%, 2% and 5% of fisher's livelihood, respectively. The study revealed that 87. 5% of the total fish production was supplied to the market. The highest average proportion of fish production supplied to the market was observed in Saint Michael (3 9. 4%) and Saint George (3 7. 8%) and the lowest in Robit Bata (22.8%). The Ordinary Least Squares (OLS) estimation shows that distance fishing ground, educational level, casual labor, credit supply, fishing trip and gillnet number are the significant determinants of the market fish. The Structure Conduct Performance (SCP) identified that the markets for fish in the study area was non-competitive type. The highest (955. 9 ETB/Qt) and the lowest (311.96 ETB/Qt) gross profit in fish marketing was obtained by retailers and fishermen, respectively. Generally, fish market in the study area seemed to be inefficient and underdeveloped. Fishers, assemblers, retailers, Fish Production and Marketing Enterprise, cooperatives, wholesalers, hotels and consumers were found to be important fish market intermediaries of the Lake Tana fishery. Fisheries development interventions should be aimed at addressing both fish production and marketing problems. The study further suggested that fish quality, fish supply, education and training, license of fishing activity and improving access to services should receive due attention in order to improve fish marketing and production in the region.