Field and laboratory experiments were conducted at Adet and Finoteselam research stations and Bahir Dar seed laboratory in 2014 to evaluate the effects of seed priming and coating on vigor, emergence, yield, yield related traits and disease reactions of bread wheat (Var., Tay). Twelve treatments were tested under field and laboratory conditions. Water and fermented cow urine were used as priming materials whereas Dynamic, Disco and genius coat were used as coating materials. RCBD with three replications was used for field experiments while CRD with four replications was used for laboratory experiment. Data like germination percentage, speed of germination, root length, shoot length, vigor index for laboratory experiment and emergence uniformity, days to emergence, days to heading, days to maturity, plant height, tiller number, leaf area index, crop growth rate, net assimilation rate, spike length, spikelet spike", seeds spike", thousand seed weight, grain and biomass yield, harvest index, septoria and Fusarium head scab scores for field experiment were taken. Analysis of variance for all parameters was computed with SAS version 9. 0 and mean separation was done using Duncan's Multiple Range Test at 1 and 5%. The mean grain and straw yield data combined across locations was adjusted down by 10% and subjected to partial budget analysis. The study revealed that germination percentage, speed of germination, vigor index, emergence uniformity, days to emergence, days to heading, days to physiological maturity, effective tiller number, leaf area index, crop growth rate, seeds per spike, grain yield and Fusarium head scab of bread wheat were significantly (p<O. OJ) affected by seed priming and coating treatments. From laboratory experiment, higher germination percentage (93. 75%) and speed of germination (34.27) was recorded by primed seeds with water. However, the root length (23.38 cm), shoot length (19.53 cm) and vigor index (3852.5) of bread wheat was higher for seeds coated with Dynamic + Disco. Under field investigation, significantly lower emergence (6.33 days), heading (67.50 days), maturity (112.83 days) time were recorded by primed seeds with water whereas significantly uniform plant emergence (98%), better tiller number (250.50 m-2), leaf area index (1.49), crop growth rate (8.56 gm-2a1, seeds spike" (56.52) and grain yield (4. 70 t ha") of bread wheat were recorded by seeds coated with Dynamic + Disco. Seeds coated with Dynamic + Disco showed 18. 09% grain yield advantage over the untreated seeds. Besides, seeds coated with Dynamic + Disco was found to be the best economically profitable combinations with a net benefit of 36,418 Birr ha ' while the second economically profitable treatment is primed seeds with water with a net benefit of 35, 122 Birr ha-1. Based on agronomic performance, disease suppressing and economic analysis, Dynamic + Disco seed coating is the best and it is recommended for bread wheat production. Furthermore, water priming is promising early emergence and better grain yield However, this experiment needs further investigation in the study areas for its reliability