Introduction: Maternal dietary knowledge andpracticeis an essential element to ensure pregnancy related outcomes and to ensure optimal gestational weight gain, reduce complications and ensures positive birth outcomes and the overall health of the mothers.Undernutritionleading global developmental challenge affecting nearly half of the world’s population and responsible for the death of 3.5 million mothers and children annuallyand thisburden results from lack on dietary knowledgeand practice in Ethiopia, so it needs further investigation on this problem. Objective:To assess dietary knowledge, practiceand its associated factors of pregnant mothers toward maternal nutrition in AddisAbaba public health centers, Ethiopia,2021 Methods:A cross sectional study conducted at Addis Ababa public health centers among363 pregnant mothers attendedANC from Aprile 1to May 30, 2021.pregnant mothers was selected by systematic random sampling technique using the total sampling frame of 3,370and collected data were checked forits completeness and then entered into Epi-data version 3.1 and exported to SPSS version 26 for analysis,model fitness tested and logistic regression with 95% CI was performed to check the association. Result:Maternal dietary knowledge was 73.9% and dietary practices 63.9% during pregnancy.Beingoccupation of dialylaboror(AOR=0.229,95%CI:(0.055-0.945)), husband’seduacational level of secondary education (AOR=4.303, 95% CI: (1.135-16.318)), family size > 4 (AOR=3.486, 95% CI: (1.553-7.823)). monthly income>7500 birre(AOR= 0.392, 95% CI: (0.158-0.972)), having chronic illness (AOR=4.116, 95% CI, (1.599-10.599)), BMI(AOR=6.082,95%CI: (1.342-27.551)), pregnancy interval (AOR=0.074, 95%CI: (0.014-0.387)), ANC visit(AOR=4.619,95CI:(1.206-17.701)), were significantly associated with dietary knowledge. Conclusion and Recommendation:The over all maternal dietary knowledge wasgood and dietary practices was poor.Womenoccupational status, husband’s education, family size, and BMI were associated with both knowledge and practices while monthly income, having chronic illness and pregnancy interval and ANC visit were only associated with knowledge.