In developing countries like Ethiopia, rural to urban migration affects the socio-economic conditions of the original areas. In the area, short-term and seasonal labor migration have been checked by other authors. However, the long-term, rural to urban migration in the country, as well as away from it, and its effect on the income of sending families, has remained unstudied. Therefore, this study focuses on assessing the effects of rural to urban migration on the income of migrant families on the origin of migrants in the Debark district, Amhara regional state, Ethiopia. To achieve the objective, 188 household heads from both the treated and control groups were selected using a multi-stage sampling technique from five kebeles of the district. Both primary and secondary data sources were used and analyzed through descriptive statistics, binary logit, and the PSM model. The primary data was collected from respondents using a structured questionnaire, FGD, and KII. Secondary data was gathered from WOFED and other relevant organizations, as well as articles, journals, and theses on the subject. Most of the respondents send their migrants to urban centers in the country, mainly towards Addis Ababa (30.14%), Bahir Dar (19.18%), and Gondar (21.92%). There are many determinants of rural-to-urban migration. Among them: family size, access to information, dependencies, education, landholding size, unemployment, livestock number,searching of better job, peer and family pressure are the major ones. PSM method was employed to estimate the effect of migration on household income. In conclusion, rural to urban migration has had a significant positive effect on the income of migrant households, yet from some FGD participants, it was found that there were also negative effects when illegal migration took place. Accordingly, the government should offer a voluntary resettlement program in the country where vacant land is available, facilitating legal migration through lobbing the destination country for better salaries for migrants. This helps migration to be worthwhile for those active labor force sending families. Keywords: Rural-Urban Migration, Debark, PSM, Effect, Income