Deposit is the most liquid money that is found within the treasury of the bank and which is prepared to be borrowed by a body in requiring of the fund. The main aim of this study was to examine factors affecting deposit growth of private commercial banks in Ethiopia. Ten private commercial banks were taken as a sample. The researcher used a purposive sampling technique to select those ten private commercial banks of Ethiopia. The data covered from the period 2010/11 -2019/20 was used for analysis. The data was collected from annual report of each private bank, annual report of national bank of Ethiopia and world bank data. Since the data was continuous in nature, a quantitative approach was used. From multiple linear regression model, fixed estimation technique was employed for regression analysis. Except life expectancy rate and branch expansion rate, all variable were statically significant at 5% significant level. Customer growth rate, capital adequacy, branch expansion, profitability, life expectancy rate and deposit interest rate affect deposit growth of private commercial banks positively. Whereas, the impact GDP growth rate was negative. The researcher concluded that, customer growth rate, deposit interest rate, profitability, GDP growth rate and capital adequacy were the most powerful variables which affect deposit growth rate of private commercial banks in Ethiopia. Finally, the researcher recommended that those private commercial banks should build their image to attract more customer and government should give a little bit of freedom to those private commercial banks to increase their deposit interest rate.