The majority of farmers in Ethiopia have limited knowledge about balanced nutrients and integrated use of organic and inorganic fertilizers with lime on acid soils. Field experiment was conducted by irrigation in 2020 to determine optimum lime, NPSB blended fertilizer and cattle manure application rates for the maximum green cob yield of maize in Koga Irrigation Scheme, North West Ethiopia. The experiment was laid out in a randomized complete block design with a factorial combination of two rates of CaCO 3 (0 and 2.5 t ha -1 ), five rates of NPSB blended fertilizer (100, 150, 200, 250 and 300 kg ha -1 ) and two rates of cattle manure (0 and 10 t ha ) which were replicated three times. The main and interaction of treatments had significant effects on phenology, growth and green cob yield of maize. Days to tasseling (63), days to silking(66), days to late milk stage(133), plant height(215.5cm), leaf area index(3.84), number of ears plant (2.58), ear length(47.4cm), number of grain per row(46.6), number of grain per cob(652.4), green cob yield ha -1 (106,348), above ground fresh biomass yield(117.82t ha -1 -1 -1 ) and fodder yield(60.62t ha ) exhibited their highest values by the interaction of 2.5t ha -1 CaCO 3 , 250kg ha NPSB blended fertilizer with 10t ha -1 cattle manure. Lime, NPSB blended fertilizer and cattle manure mostly in combination were having positive correlation impacts on the growth parameters and finally resulted in higher green cob yield. The highest (305,154.3ETB ha -1 ) net benefit was obtained by 2.5t ha -1 CaCO 3 and 250kg ha -1 NPSB blended fertilizer with10t ha -1 cattle manure. Generally, combine application of 2.5t CaCO 3 ha -1 , 250 kg NPSB blended fertilizer ha -1 and 10t cattle manure ha -1 increased significantly green cob yield by 48.93% against the NPSB blended fertilizer alone (100 kg ha -1 ). Integrated application rate of 2.5 t CaCO 3 ha -1 1 and 10 t cattle manure ha -1 -1 , 250 kg NPSB blended fertilizer ha were increased economic feasibility for green cob yield by 50.9% over the NPSB blended fertilizer alone (100 kg ha -1 ). Combined use of 2.5t ha , NPSB blended fertilizer at 250kg ha -1 and cattle manure at 10t ha -1 is found to be economically optimum application rates for production of green cob yield in Koga Irrigation Schemes and other similar areas with problem of soil acidity. However, this result is single year and location, it should be repeated in many sites and years. Keywords: Cattle manure, green cob yield, lime, NPSB blended fertilizer, soil acidity