Agriculture is a basic limiting factor for achieving food security in Ethiopia because more than 80% of the country's population depends on it for its livelihoods. In many part of the country, frequency and distribution of rain fall, which is the principal source of water for agricultural crop production, is becoming more unreliable and inadequate with the occurrence of drought which make irrigation farming more valuable. Irrigation farming also has both direct and indirect effect on household food security. The purpose of this research was to analyze the effect of small scale irrigation on rural household food security based on data collected from 185 sample rural households in Goncha Siso Enesie district Amhara regional state, Ethiopia. A multi-stage random sampling technique was employed to select sample households. The combination of analysis such as descriptive analysis, household food balance model and binary logit regression model were employed to reach sound conclusion by using data collected from primary and secondary sources. The survey result revealed that out of all sampled households, 74.1% (137) were food secured while 25.9% (48) were not food secured. There was high gap in food calorie availability ranges from 753-6659 kcalladult equivalent/day in the study area. Of the 84 irrigation users and 101 non-user sampled households, 84.5% and 65.3% were food secured respectively. The study found that education level of household head, household size, farmland size, access to irrigation, access to credit service, access to extension service and participation in nonfarm activities were the determinant factors of household food security in the study area. The study also identified majorproblems associated with small scale irrigation in the study area that are lack of input supply, lack of water management, lack of efficient marketing system, limited extension service, less attention and support to establish and strengthen irrigation users association, decline of selling price at peak harvesting time of irrigation products, water logging and loss of soil fertility and occurrences of crop pests and diseases. Small scale irrigation has direct and indirect positive effect on enhancing household's income and food security, which needs focus for its promotion and improvement from concerned development partners and policy makers.