The purpose of this study was to investigate the effects of plyometric training on selected technical skills performance of u-15male handball project players at Borena woreda Ethiopia. The total subject for the study were twenty-four (n =24) male handball trainees of Borena woreda handball project players in Ethiopia 2013 E.C. The study populations were little; all are taken as a sample by using comprehensive sampling technique. Through randomization method trainees segregated in to two groups, an experimental group (n=12) and a control group (n=12). The experimental group (EG) performed twelve-week low to moderate plyometric training, 3-days per week for a total of 45 minutes and the control group (CG) did only their regular handball training 3 days per week for 60 minutes duration. The data was collected through field technical skill tests (jump shoot test to jumping accuracy, accuracy throw test to passing accuracy and obstacle dribbling test to speed dribbling).The data were analyzed by using Paired sample t-test and Independent sample t-test statistical tools SPSS version 23 with significance level of 0.05.Based on the analyzed data, the pre-posttest performance of EG were significantly improved in passing accuracy, shooting accuracy and speed dribbling (p=0.000, p<0.05).similarly, the independent t-test shows the posttest performance of these variables in EG were significantly more improved than posttest result of CG (p=0.000, hence p<0.05). The results of this study shows that 12 weeks plyometric training improves shooting accuracy, passing accuracy and speed dribbling of u-15 male handball project player’s technical skills performance. Therefore the study recommend that coaches should give concentration to plyometric training in coaching