By using mixed approach the study investigated the practice and challenge of implementing physical education practical session in Secondary Schools of Awi zone. A total of 186 participants; 160 students, 20 teachers 4 principals and 2 supervisors were selected by using simple random sampling, comprehensive and purposive sampling techniques respectively. Three data gathering tools questionnaire, interview and observation were used. Data were analyzed using descriptive and inferential statistics and narrative descriptions. Results from students’ and teachers’ questionnaire depict that respondents show a low level of agreement on the practice items towards the practice of and challenge of implementing physical education practical session in Secondary Schools of Awi zone. This study investigated how demographic variables; sex, grade level, age and positions affected the practice of and challenge of implementing physical education practical session. Of the variables sex, age, grade level and positions were significant predictors of statistical variation towards the implementation of physical education practical session in Awi zone. From the qualitative data, some of the common major problems identified are listed as follows: shortage of budget to fulfill those materials that are very important for physical education practical sessions, less attention is given to physical education practical sessions from the administrative body, lack of sport fields etc. Thus, it is recommended that Physical education subject has to be perceived and treated equally with other subjects by time allotment; budget, with man power, facilities and equipment’s in the school. Key words: