The study was conducted to evaluate the inclusion of dried student’s cafeteria leftover (DSCLO) on feed intake, nutrient digestibility, body weight change, feed conversion efficiency, carcass characteristics and economic benefits of Washera sheep fed with Desho grass as a basal diet and supplemented with varying proportion of concentrate mix (CM). Dried student’s cafeteria leftover collected from Bahir Dar University was dried and ground in mill house. In order to assess the feed safety of DSCLO, various microbiological analyses were performed following standard microbiological guideline. Various microbes were detected and enumerated such as: Staphylococcus aureus, Yeasts and Molds, Coliforms, Fecal coliform and Escherichia coli, Salmonella and Enterobactreacea. Aerobic plate count yielded 2.36x106 CFU/g, enumeration of Coliforms, Enterobacteriaceae and Yeasts and Molds yielded 2.15x103, 6.5x103 and 1.2x106 CFU/g of DSCLO, respectively. Fecal coliforms and E.coli were determined to be <1.8 MPN/g of DSCLO. S. aureus and Salmonella were not detected in the DSCLO samples. The DM, CP, ash, NDF, ADF and ADL content of DSCLO were found to be 92%, 12.72%, 4.34%, 20%, 13.18% and 6.59%, respectively. Twenty-five intact Washera male sheep with mean body weight of 21.9±1.01 Kg (mean ± SD) were allotted randomly to five dietary treatment groups in a randomized complete block design (RCBD) each with five replications. The dietary treatments included: 0% DSCLO+100% CM (T1), 25% DSCLO+75% CM (T2), 50% DSCLO+50% CM (T3), 75% DSCLO+25% CM (T4) and 100% DSCLO+0% CM (T5). The experiment consisted 90 days feeding trials after quarantine and adaptation period to the experimental feed. Digestibility was done after the feeding trial for 4 days of acclimatization period to fecal collection bags prior to collection period of 7 consecutive days. At the end of the experimental period all sheep were slaughtered