Salmonella infections originating from chicken table egg are one of the major causes of food-borne illnesses and presence of drug resistant Salmonella is one of the main public health concerns world-wide especially in developing countries like Ethiopia. Across sectional study was conducted from November 2018 to April 2019 in Bahir Dar Town to identify Salmonella isolates from table egg and associated risk factors; to determine their antimicrobial resistance profile. A total of 157 egg samples were collected from Bahir Dar Town poultry farm and market by systematic random sampling technique. Hence, each egg was sampled twice for egg surface and internal content, totally 314 samples were processed for isolation of Salmonella by using conventional bacteriological methods. Antimicrobial sensitivity test was performed to 10 selected antibiotic discs by disc diffusion. Questionnaire survey and observation was administered to observe associated risk factors. The overall level of Salmonella isolation rate in current study was 2.2 %. Isolation rate of Salmonella among egg shells were 3.8% from the open market and 1.3% from the poultry farm. About 3.9% of Salmonella isolation rate was observed from internal contents of farm eggs. Isolation rate of Salmonella between sample site and sample type was not statistically significant (p = 0.69) and (p=0.702) respectively. All Salmonella isolates were susceptible to ciprofloxacin and gentamycin; however, all of them were resistant to ampicillin, tetracycline and cephalothin. All isolates were developing multiple drug resistance. There was poor egg handling practice and poultry farms that practice proper use of foot bath was 0.118 times less likely contaminate table egg as compared to counterparts (p=0.012); Even though the prevalence of Salmonella was low in current finding, isolates were develop multidrug resistance. Therefore, proper egg handling, proper use of foot bath and rational antimicrobial usage should be practiced Key words: antimicrobial sensitivity; Bahir Dar; chicken egg; Ethiopia; Salmonella