The general objective of this research was to assess practice, challenges and opportunities of students with disabilities (SWDs)in the traditional church education of Ethiopian Orthodox Tewahido Church in the area of Bahir Dar city. Conceptually it was delimited to students with physical and visual impairment. Qualitative research approach and case study design was employed. Pragmatism paradigm was used to this study. The sampling techniques were also applied both purposefully, available and snowballing. The data collection instruments used was interview and focus group discussions by using recorder. The participants were SWDs in traditional church education (TCE), teachers and church leaders. The data was analyzed following the analysis procedures organizing, transcribing, coding, and developing themes using thematic analysis. The finding of this research reveals that SWDs in the traditional church education are surrounded with enormous challenges. These problems are mostly related with teaching materials, infrastructure of the centers, psychological, basic needs and financial problems. The existences of these challenges have forced them to be hopeless, hate the program, and ultimately withdraw from their education. And their withdrawal has led them to be street vendors, beggars, addicted to drugs and involved in to crimes of robbing. They also become to be reasons for social problems in their community. The main opportunities in the Ethiopian Orthodox Tewahido Church Education for students with disabilities are having strong relationship among other STDs irrespective of race, color, economic background and status of disability. They see each other as family members. Teachers’ effort in engaging SWDs in to the traditional church education through providing of readers, counseling and considering them in any cases were supportive. The support they received from the community members in providing food was also encouraging. The education has also made them to be strong spiritually. However, based on the findings the researcher recommended, traditional church education does not received full attention on strengthen in terms of learners and learning institutions. Hence, Bahir Dar Hager Sebket as one of the responsible association needs to strengthen the church education.