Synthesizing new biologically active compounds sets up the efforts made in overcoming the alarming problem of microbial resistance to antibiotics. In line with this, a copper (II) coordination compound of 2, 2`-bipyridine and adenine were synthesized by the reaction between a cooper (II) salt and ligands in molar ratio (1:2:1) ,where M=Cu and the ligands are 2, 2`-bipyridine and adenine. The compound was characterized by using halide test, conductance measurement, solubility test, melting point and spectroscopic analyses (ICP-OES, FTIR, and Uv-Vis). Square pyramidal geometry with formula [Cu (bip)2(Ad)]Cl2.2H2O is proposed. The spectroscopic data suggests that the ligands are coordinated with the metal ion via nitrogen donor centers. The complex was tested for antibacterial activity against two Gram positive Staphylococcus aureus and Streptococcus pyogenes and two Gram negative Escherichia coli and Klebsiella pneumonia bacteria. The complex is found to be active against all the tested bacteria even against the Gram negative bacteria (Escherichia coli, Klebsiella pneumonia) the complex showed lower activity than the reference antibiotic drug(Gentamycin). Key words: Cu (II) chloride salts, copper (II) complex, antimicrobial activity, 2, 2`-Bipyridine, Adenine.