This study was conducted in Woyebela watershed Goncha Siso Enssie district, East Gojjam, Northwestern Ethiopia. The objective of the study was to assess the effect of soil and water conservation practices on biophysical attributes, selected soil physico-chemical properties and livelihood of the people in the watershed. Data was collected through semi-structured interviews, key informants, focus group discussion, field observation, laboratory analyses, field measurements and using secondary data. In addition, using Google earth with 30 meter resolution taken on December 2008 and April 2015. Data was analyzed using qualitative and quantitative analytical methods entered into SPSS software. The results revealed that SWCP significantly (p<0.05) influenced bio-physical condition of the watershed. The slope was transformed significantly from 15.9 % o 12.6 % slope after SWCP. Between 2008 and 2015 the primary cultivated land decreased by 0.23 % of its original cover. Whereas, grazing land and plantation land increased by 1.09 and 6.7 % of their original area respectively. On the contrary, wood land decreased in extent by 7.62 %. Despite the fact, 61.3 % of respondents has access to drinking water supply and sanitation service and field walk to fetch water were decreased after SWCP. Laboratory results found a significant difference between soil physico- chemical properties of conserved and non-conserved watershed. Non-conserved watershed had the highest mean value of bulk density (Bd 1.15 g/cm3) with the dominante clay loam soil texture (54 %) and lowest mean value of soil organic matter (1.61 %) total nitrogen (N), (0.1%), available phosphorus (4.3 ppm ) and potassium content of soil (1.2 cmol/kg). Whaer as , the lowest values of Bd (1.07g/cm3) with the dominate clay soil texture (40 %) and high value of organic matter (2.7%), total N (0.16%), available phosphorus (5.8 ppm) and potassium content of soil (1.32 cmol/kg) were recorded in the conserved watershed with similar slope classes to that of non- conserved watershed. SWCP has agerat role to improved the livilhood of the people by improving the crop yiled, animal product and diversified incame generation activites. Filed maserment showed that, the current yield of crop were 18/q/ha, teff 39 q/ha wheat and 40.2 q/ha maize. this indicat that, thire is grian yiled improvement after SWCP. 18 % and 35 % of respondant were feed thire livestock improved foraged and mixied with crop residue respectively. From the results of the study, it is possible to conclude that SWCP had positive effects on the biophysical, soil physico-chemical properties and livelihood change under subsistence farming systems of the study area.