There are various parameters during yarn production which can influence the quality of yarn. Two of them are the traveler weight and spindle speed on a ring spinning machine. This work was undertaken to study the effect of traveler weight and spindle speed on the quality of 21ˢ Ne 100% cotton carded yarn. The C-type travelers were used for this study. Five different traveler 31.5, 35.5, 40, 45, and 50mg weights were used and tested at the spindle speed of 12000, 13000 and 14000 rpm. The yarn samples obtained by using different traveler’s weights and spindle speed were tested for hairiness, amount of twist, tensile strength, and elongation %. Results showed that there was a decrease in the yarn hairiness as the spindle speed and traveler weight at 14000rpm and 50 mg respectively. At the spindle speed of 12000 rpm and traveler 50 mg the optimum tenacity and twist were achieved whereas the spindle speed13000 rpm and traveler 31.5 mg gave optimum elongation.