The study was designed to investigate the Comparative Effectiveness of manual hand drawing and CAD on secondary school student’s visualization a case of Ras Amoraw Wubneh Tessema general secondary school in Tach Armachiho woreda of Gondar, Amhara region, Ethiopia. The objective of the study was investigating Comparative Effectiveness of Manual Hand Drawing XIII and CAD on Secondary School Student’s Visualization and to assess the relationship between time and score among the two method of teaching. The study was a pretest, posttest, non-equivalent control group of quasi-experiment. Two research questions tested at (0.05) level of significance, guided the study. The sample size was 50 from which 30 students are assigned to manual hand drawing method and 20 students are assigned to CAD method and both groups are pre-tested. The instruments used for data collection20 multiple choices & 4 multiview drawing of Purdue Visualization of Rotation Test (PVRT) and mental rotational test are prepared by the researcher. The post-test was administered after students had completed 12 weeks of the courses showed no significant difference in either group's ability to do visualization of multiview drawing. Mean and ANOVA were used to analyze the data collected by using IBM SPSS statistics version 26. The study found no statistical significant effects of CAD methods and Manual Hand Drawing method on the ability of the students of visualization and this visualization of technical drawing concepts can be taught with CAD as well as with Traditional Manual Hand Drawing tools. The study recommended that, since CAD is as effective as Traditional Teaching Methods and is the way of the future, this method be used in teaching visualization of multiview drawing