Now a day plant based fiber composites in future may become materials to replace synthetic fiber polymer based composites due to their low cost, low density, lightweight attractive specific properties, high specific strength and no health risk, easy availability in some countries and renewability. The main goal of this study is to Experimental investigations of mechanical properties of sisal natural fiber and glass fiber hybrid composite material quality and performance of plant natural based composites can further be improved by adopting efficient engineering techniques. An 8% sodium hydroxide was used for further lignin, hemicellulose and other fiber remnants removal for the improvement of bond and interfacial shear strength of the sisal fiber. Next, SGREC turned into fabricated with 29% fiber quantity fraction and 71% matrix quantity fraction in a [0/90] s laminate orientation. Of this total fiber volume, the composite is fabricated in different sisal to E-glass fiber ratio using hand lay-up vacuum assisted technique. Then tensile, compression and impact test were carried out. A sisal to E-glass fiber ratio of 25:75 was found a higher tensile strength; whereas sisal to E-glass fiber ratio 25:75 had higher compression strength. Similarly, a sisal to E-glass fiber ratio of 25:75 had higher impact for all the tests carried out. The result showed that the sisal fiber experienced a substantial changes occurred during alkaline treatment, and good result also attained from interaction among sisal and E-glass with epoxy. Furthermore, it is found out that the sisal and E-glass fiber ratio of 25:75 output can have a potential to be used for wing part spar material. Keyword: Sisal fiber, E-glass, Handy layup, Tensile strength, Impact strength and compression strength.