The most significant constraint on construction projects is time. However, delivering construction projects in Ethiopia within the agreed contract time is becoming continually challenging. As a result, the anticipated services are delivered with too much delay to provide the intended purposes. To manage projects in an effective and efficient manner, this approach needs to be improved. Proper construction work scheduling development and implementation is one of the vital factors that contribute to a project‘s success. In this context, the general objective of this study was assessment of construction work schedule development and implementation practice on public building project monitoring by road and building design and construction supervision work enterprise. To achieve the objectives of this study data were collected using both primary and secondary data through identifying variables from literature reviews, questionnaires, desk study, interviews, and data from reports. Multiple linear regression models, correlation methods and ranking the factors in terms of degree of effect through descriptive data analyses with help of Statistical Package for Social Science (SPSS) version 22 software was employed for collected data analysis. According to the research's findings, the most crucial tasks for the development and implementation of a construction work schedule were to define the project's work period, understand the full scope of the work, and revise schedule depending on project progress. According to research findings, all public building construction projects fell behind schedule. Four categories of factors were identified as having a significant impact on the public building project's construction work schedule performance those related to the contractor, consultants, clients, and external factors, with predicted incidence rates of 0.461, 0.215, 0.161, and 0.161 respectively. The research findings also suggested improvement methods for schedule performance which contractor should manage his financial resources, plan cash flow, and develop strategy and policy how to development and implementation construction work schedule were the first rank. Finally, recommendations were proposed that enables to improve construction work schedule development and implementation practice. Keywords: Construction work schedule, public building project, Statistical Package for Social Science (SPSS)