Groundwater is the primary source of domestic, agricultural and industrial use in many regions of the world. this study aimed to use the time and cost-effective remote sensing (RS) and geographical Information system (GIS) techniques for assessing groundwater potential Zone in East Belesa District area. Thematic map derived from Landsat 8, existing borehole, Digital Elevation Models (DEM), and Rainfall data were utilized in this research. The thematic layers considered in this study were soil texture, Geology, geomorphology, drainage density, lineament density, rainfall, slope, and land use/cover. The weights have been assigned according to their relative importance in groundwater occurrence and the corresponding normalized weights were obtained based on Saaty's analytical hierarchy process. The thematic layers were finally integrated using Weighted Overlay analysis, then to produce a groundwater potential zone map of the study area. Three different groundwater potential zones were identified;40.80% High, 58.57% moderate, and 0.63% Low groundwater potential zones have been identified. The resulted groundwater potential zoning map was validated using NDWI, NDMI, and 53 water point data. Interestingly 36 data were overlaid.9 water point data were validated on the high, 18 water point data were overlaid on Moderate zone, and 9 water point data overlaid in low potential zone. Generally, in this study, it was found that high groundwater potential was found on the north-western side of the study area; so, groundwater can be exploited more in these areas. Hence to meet the increasing demand, new well fields may be formed in high groundwater potential zones, especially on the northwestern side of the study area. Keywords: AHP ,Groundwater potential, GIS, Remote Sensing