Drilling is the most generally perceived machining process in the world and also in our country Ethiopia whereby the operation incorporates making round openings in metallic and non-metallic materials. Around 75% of all metal cutting method is of the drilling operation. The growth of Ethiopia manufacturing sector depends largely on its productivity & quality. Multiple-spindle drilling machines are used for increasing the mass production rate and saving of important time which are required for producing the holes with help of drill. The aim of this thesis was to design and fabricate of multi spindle drill machine that can drill three holes at a time up to 20 mm diameter. The material to be used for the machine to be designed is mild steel for gears and 40C8 steel for shaft. There are two types of parts designed and purchased parts. Process parameters have been selected for different components, material was selected for all components and stress and force analysis for shaft and tooth wear analysis for gears have been done for investigating the designed parts are safe for fabricating. Then, the designed parts to be fabricated. Fastening, joining, fitting method, drilling, smoothing, cutting, grinding method were used to fabricate this machine. Proper available tools and equipment‟s have been used, like welding machines, grinding machine, drilling equipment‟s. Measuring tools, testing tools, safety tools. This machine has different components spindles, gears, bearings, bearing housing, plate and chunk. for drilling This fabricated machine was tested experimentally on Aluminium as a target material, the result was compared to conventional drilling machine. Comparison was made in terms of drilling time, job handling, multiple operation possibility, quality and productivity. The designed machine is functional and effective to drill multi hole on targeted material. KEY WORDS: Chunk, Gear, Manufacturing, Multi drill, Productivity, Spindle