The issue of divorce is an increasing social problem that has become a topic for discussion in recent times. Even though divorce highly affects divorcing couple and their children as well as societies at large, in Ethiopia, adequate studies have not been conducted on the effect of divorce in general and children's schooling in particular. This study was aimed at investigating the schooling experiences and challenges of children from divorced families in Fasilo secondary school. The study was guided by a qualitative case study design. The data were collected from four divorced parents, eight children from divorced families, and six teachers through semistructured interviews, focus group discussions, and document analysis. Children and parent participants were selected via snowball sampling technique and teachers were selected via purposive sampling technique. The finding shows that children from divorced families have faced many challenges. Children had exposed to feelings of anxiety, feelings of confusion, and a negative attitude about marriage. The economic problem is one of the challenges faced by students from divorced parents. Children's basic needs and academic facilities had not been fulfilled adequately. Children had less ability to socialize with their parents and peers, they were discriminated against and marginalized by peers, stepfamilies, neighborhoods, and the community. Children from divorced families have low parental educational support, less classroom attention, and poor academic performance. Finally, the study forwarded relevant recommendations to minimize the challenges of children from divorced families on parents' open discussion about child care and support, giving time to children through regular visits. Training and counseling services given by school guidance and counselors and stakeholders' active participation in the process of supporting children and protecting them from divorce-related problems are recommended to reduce the effect of divorce on children's schooling.