Environmental and ecological changes in the course of time have threatening the very survival of the human race on earth. The transformation of the natural world by human action has an effect on both the nature and the people. Such phenomenon has given way to the evolution of modem environmental history in the 201hcentury. Accordingly, this study as part of the environmental hi~tory deals with the malaria epidemics in in the former Qolla-Daga Damot Awrajja. Population movement and ecological changes were the major factors that contributed to the outbreak of recurrent malaria epidemics across many regions in Qolla-Daga Damot Awrajja. Ber-Salaqo, in Jabi-Tahenan Warada, served as the dissemination center of malaria and recurrent malaria epidemic outbreaks. The agricultural productivity of Ber-Salaqo brought both the attention of the government to the agricultural development programs and the nearby woredas people, such as Quarit and Daga-Damot where lands are inconvenient for agricultural practices. Therefore, tremendous ecological changes were brought to Ber-Salaqo and which in tum brought changes in the pattern of malaria transmission in the region. The wide spread of the malaria malaria infection in the Qolla-Daga Damot districts was effected by the returnees with the malaria paRasite to the malaria receptive areas of Quarit and Daga-Damot. Therefore, this thesis analyze the ecological changes, population movement from the daga regions to qolla with in the awraja itself along with the vagaries of weather as the major causes to the spread of malaria transmission and recurrent malaria epidemics m the study area .