Introduction: worldwide anemia during pregnancy is a public health problem, especially in developing countries. In most of the cases, anemia is largely preventable and easily treatable if detected in time. However, anemia remains one of the causes of maternal and neonatal morbidity and mortality.so it is still the problem in the study area and needs intervention to reduce factors associated with anemia Objective: The aim of this study was to assess factors associated with anemia among pregnant women who attended antenatal care in governmental health facilities at Pawi district, northwest, Ethiopia 2020. Method: Institutional based cross-sectional study was employed among 400 pregnant women from February 1-30/2020 who attended antenatal care in governmental health facilities at Pawi district. The data was collected by structured interviewed questionnaire, and entered into a computer using Epi data version 4.5, edited and analyzed using Statistical Package of Social Sciences version 23. Bivariable and multivariable logistic regression analyses method was employed to estimate the crude and adjusted odds ratio among with corresponding confidence interval of 95% and P value of less than 0.05 was considered as statistically significant. Result: The overall prevalence of anemia among the pregnant women in the study area was 32.8% (95% CI:28.2-37.3%). The Multivariable logistic regression analysis showed that residence living in rural [AOR=3.19, 95% CI, 1.84-5.52], low monthly family income [AOR=6.51,95%CI 2.10-20.16], History of abortion before current pregnancy [AOR=5.28, 95% CI ,3.04-9.18] Coffee intake always after meal per day [AOR=3.53, 95%CI,1.67-7.51] have significant association with anemia. Conclusion: In this study pregnant women who had anemia was high. Residence living in rural, low monthly family income, history of abortion before current pregnancy, and coffee intake always after meal per day among pregnant women were significantly associated with anemia. Key words; Anemia, factors, Pawi district and Pregnant women