Non-Compliance to Lymphatic Filariasis Preventive Chemotherapy and Associated Factors, Jawi District, Amhara Region, Northwest Ethiopia: Case Control Study

Fetene, Mihretu

dc.contributor.author	Fetene, Mihretu
dc.date.accessioned	2022-06-28T08:21:37Z
dc.date.available	2022-06-28T08:21:37Z
dc.date.issued	2021-06
dc.identifier.uri	http://ir.bdu.edu.et/handle/123456789/13830
dc.description.abstract	Introduction: Lymphatic Filariasis is a human disease caused by parasitic helminths mostly by Wuchereria bancrofti. To eliminate Lymphatic Filariasis, the World Health Organization recommends a combination of preventive chemotherapy using Ivermectin and Albendazole through mass drug administration. The mass drug administration is given annually to the entire population living in endemic areas irrespective of the individual infection status. In Jaw, after five rounds of drug distribution, the district failed in the Pre- Transmission Assessment Survey. This may be partially related to non-compliance of the annual mass drug administration treatment by the community members. Objective: The aim of the study is to assess non-compliance to lymphatic filariasis preventive chemotherapy and associated factors, in Jawi District, Amhara region. Methods: An unmatched Case- control study design with Mixed method, quantitative and qualitative method were used. A structured questionnaire was developed and used for data collection. For quantitative data, Systematic sampling technique was used to select 348 case and 348 controls while in-depth interview was conducted on eight community drug distributors, three health extension workers and one expert for qualitative study. SPSS Statistics Version 26 was used, the data were organized in tables, graphs and described with percentage. Bivariable and multivariable logistic regressions were used for analysis to identify the associations between dependent and independent variables. Qualitative data were analyised thematically. Results: A total of 690 (99.1%) participants, 345 cases and 345 controls, were included in the study. Younger age [AOR=1.60 (95% CI: 1.10-2.33)], Male sex [AOR= 0.64 (95% CI: 0.44-0.93)], knowledge of the disease [AOR= 0.55(95% CI: 0.38-0.81)], not use of long-lasting insecticide-treated nets [AOR= 2.13 (95% CI: 1.18-3.83)], no fear and experience of side effects [AOR= 0.43 (95% CI: 0.23-0.76)] and not participate during community drug distributers, selection [AOR 2.58, 95%CI 1.70-3.91] were found to be predictors for non-compliance for lymphatic filariasis preventive chemotherapy treatment. Conclusion: Ivermectin with Albendazole treatment non-compliance was influenced by different potentials factors. Age, Gender, knowledge on the disease, fear and experience of side effects, use of long-lasting insecticide nets, and participation in CDD selections were the predominate factor for the non-compliance of treatment. Key words, Ivermectin with albendazole, lymphatic filariasis, non-compliance, preventive chemotherapy	en_US
dc.language.iso	en	en_US
dc.subject	Health System Management and Health Economics	en_US
dc.title	Non-Compliance to Lymphatic Filariasis Preventive Chemotherapy and Associated Factors, Jawi District, Amhara Region, Northwest Ethiopia: Case Control Study	en_US
dc.type	Thesis	en_US