Introduction: A traditional Bonesetter is a lay practitioner who deals with the management of musculoskeletal injuries (fractures, dislocations, etc…) along with their complications. They of-ten use splints made from a split of bamboo or strips of wood tightly bound about the limb, oc-casionally including local joints. Individuals who face musculoskeletal injuries utilizes both traditional bonesetters and modern health institutions. Traditional bonesetting is associated with more treatment related complica-tions in its practice while modern health institutions deploys sophisticated techniques of treat¬ment which results in satisfactory outcomes. Objectives: The objective of this study is to determine the proportion of the community who prefers either traditional bonesetting or modern health care system as primary treatment desti-nation for musculoskeletal injuries and to identify factors, which modulate it. Methodology and Materials: A community-based cross-sectional study was conducted in Bahir Dar, Ethiopia, from November 10 to December 20, 2020. A systematic random sampling tech-nique was deployed for sample selection and data was collected using a pretested structured questionnaire. Finally, collected data was coded, fed to the computer using SPSS version 26 software. Simple descriptive analysis and binary logistic regression analysis was deployed to identify associated factors, for which chi-square assumption was fulfilled. Result: More than half, (208, (53.5%)), the study participants preferred traditional bonesetting as primary treatment destination for possible musculoskeletal injury. The multivariable logistic regression revealed that gender, religion, educational status, previous TBS visit and previous hospital visit were significantly associated with TBS preference for MSK injury treatment. Accessibility, cheap and negotiable price, and community trust to TBS positively affected its preference for possible MSK injuries. Conclusion: The community of the Bahir Dar city prefers TBS as primary treatment destination for musculoskeletal injuries. Previous visit to TBS significantly promotes further visit for future incidents in demand, whereas previous treatment to health facilities for similar incidents de-creases the chance of preferring TBS. Key words: patronage, traditional bonesetting, musculoskeletal, bamboo splint