Back ground: Instrumental vaginal delivery is aprocedure used as an alternative to caesarean section reduce the caesarean section rate. However; there is no information on the maternal outcome of instrumental vaginal deliveries and associated factors in the study area. Thus, this study is aimed to fill the paucity of information in the study area that play vital role to reduce maternal and neonatal morbidity and mortality. Objectives: To determine the maternal outcome of instrumental vaginal deliveries and associated factors among mothers who gave birth in DMCSH, East Gojam Zone, and Amhara, Ethiopia June 30, 2017 to July 8, 2020 GC. Methods: A hospital based - cross-sectional study was conducted among others reviewing maternal cards, selected by a Simple random sampling technique that gave birth by instrumental vaginal delivery from June 30, 2017 to July 8, 2020. Data was collected using a pretested checklist and the data was checked for its completeness. Then the data was edited, coded, entered, cleaned and analyzed using SPSS version 25. Data presented by using frequencies, percentages and tables. P-value <0.05 was considered as statistically significant Moreover, logistic regression model was use to assess the presence of associations between variables. Finally, interpretation, discussion and recommendation made based on the findings of this research Results: In this study total 624 mothers who gave birth instrumental vaginal delivery were studied of those mothers who underwent instrumental vaginal delivery 394(65.4%), 208(34.6%) were vacuum and forceps delivery respectively. The proportion of unfavorable maternal outcome was 21.8%. Un favorable maternal outcome is higher due to forceps 76 (36.5 %) than vacuum 55 (14%). Regarding component of analytical study mothers came from out of out of debremarkos were about 3.6 times more likely to have un favorable maternal outcome than town (AOR,3.6;95%CI: 1.95, 7.526). Primipara mothers were about 4.6 times more likely to have un favorable outcome than multiparas (AOR :4.6;95%CI: 1.636, 12.865). mothers referred from other health institutions had 7.7 times more likely to have un favorable outcome thane who has from town (AOR 7.733 , 95% CI:03.681, 16.247) . Mothers who had given birth neonatal birth weight>4000grams had 5.6 more likely to have unfavorable maternal outcome than 2500-3999 grams. ((AOR; 5.6; 95% CI:1.435,21.848). Mothers who had no episiotomy were about 3.8 % more likely to have unfavorable maternal outcome those who had episiotomy (AOR, 2.789 ,95% (1.414-5.385). Forceps delivery 5.7 more likely to have unfavorable maternal outcome than vacuum delivery (AOR, 5.692; 95% CI:2.821,11.484) Conclusion Unfavorable Maternal outcome related to instrumental vaginal delivery is 21.8% . Maternal residence, parity, hospital visit type, neonatal birth weight, Station during instrumentation, episiotomy and type of IVD were the independent factors associated with maternal outcome adjusted for the other dependent factors. Key words: Cross-sectional study; instrumental delivery, maternal outcome