Pooled Prevalence and Associated Factors of Precancerous Cervical Lesion Among Women in Ethiopia

Dereje, Zena

dc.contributor.author	Dereje, Zena
dc.date.accessioned	2022-04-13T10:05:06Z
dc.date.available	2022-04-13T10:05:06Z
dc.date.issued	2020-02
dc.identifier.uri	http://ir.bdu.edu.et/handle/123456789/13520
dc.description.abstract	Background: Cervical cancer remains the most common cancer of women worldwide. Its burden is more serious in the developing countries. It is also the second common deaths of women in Ethiopia followed by breast cancer. Even though, some studies were conducted to assess the prevalence and associated factors of precancerous cervical lesion among women in Ethiopia, a variation in reported prevalence across the studies were observed. Objective: This study was intended to determine the pooled prevalence and associated factors of precancerous cervical lesion among women in Ethiopia. Methodology: Published and unpublished articles reported from 2010 to 2019 were systematically searched using a comprehensive search of electronic databases including PubMed, Congress Library, and Web science core collection and Google scholar for grey literature. The methodological qualities of included studies were evaluating using Joanna Briggs Institute meta-Analysis of Statistics Assessment and Review Instruments by two independent review authors. The pooled prevalence estimate was calculated using MedCalc software-version 19.0.7 and the pooled odd ratios for predictors was calculated using RevMan software version 5.3. Results: The pooled prevalence of precancerous cervical lesion among women in Ethiopia was 13.4%, 95% CI (10.63, 16.37%). Statistically significant heterogeneity between studies was detected (I2=83.10% (p<0.0001). Among all measured associated factors: numbers of women’s’ life time sexual partners >1, OR=2.50,95% Cl (3.70,4.76), being HIV positive women, OR=2.44,95% CI (1.33,4.61), women having history of STI, OR=1.99,95% CI (1.02,3.87), women’s income <1000 birr, OR=1.78,95% CI (1.19,2.65) and women had experience of contraceptive use, OR=2.32, 95% CI (1.75,3.43) were had statistical significant association with precancerous cervical lesion among women in Ethiopia Conclusion: The pooled prevalence of precancerous cervical lesion among women in Ethiopia was high as compared to the 5-year worldwide cervical cancer prevalence (1). Moreover; there was a variation of cervical cancer reports across studies. Therefore; consistently reporting of this information is important for researchers to enhance future studies and also it is useful for better understanding of cervical cancer burden in Ethiopia by policy makers and practitioners for early prevention, diagnosis, and treatment of the disease. Keywords: Precancerous cervical lesion, Cervical Cancer; Cancer of the Uterine Cervix; Cervical Neoplasms; Cervix Neoplasms.	en_US
dc.language.iso	en	en_US
dc.subject	Biostatistics and Epidemiology	en_US
dc.title	Pooled Prevalence and Associated Factors of Precancerous Cervical Lesion Among Women in Ethiopia	en_US
dc.type	Thesis	en_US