Crane hook is a vital component in the loading-unloading phenomena. Accumulation of massive amount of stress on crane hook due to repetitive loading unloading circumstance on the main hook of a crane, corrosion, wear, induced high-stress is the most frequent cause of problems, and which could ultimately result in its failure. Considering the fact that crane hooks are highly responsible elements exposed to failure nevertheless, there are little researches that have been done on the optimization and fatigue life of crane hooks using composite materials. To plunge the induced stress, weight, and corrosion of crane hooks, design, analysis, and optimization should be studied. This study aims to Design a crane hook with minimum induced stress, less wear rate, minimized weight, non-corrosive, and having a capacity to handle one ton of material for a long life span without failure. By substitute typical materials that were used before into highly ductile composite material called S-glass reinforced polyester composite. Thus analytical, FEA, and experimental analyses were conducted. Each pass-segment and stress at fibers of crane hook was determined using analytical methods and FEA that perform by percentage error evaluation. Two-D and three-D models of crane hook modeled primarily, based on analytical data’s by the usage of SOLIDWORK 2021. ANSYS software discovers high-stress concentration regions. Taguchi-based Gery Relation Analysis Optimization techniques are used to reduce failures and multi-objective optimization conducted from analyzed outcomes. Depending on induced stress in the inner fiber, outer fiber, and weight of crane hook results from different cross-sections that affect the stress and weight reduction of the crane hook. Thus based on optimal parameters; by changing fiber orientation and arrangement the 3D hook was modeled and the static structure was studied by ANSYS. Finally, the actual crane hook was manufactured by the Hand lay-up method using optimal data and selected material and followed by a destructive kind of test on sample specimen, load proof test (LPT), and study the effects of fiber orientation and arrangement. Keywords: Crane Hook, Taguchi, GRA, S-fiberglass, Load proof test (LPT)