Background: Goiter is an abnormal enlargement of the thyroid gland due to inadequate intake of iodine and goitrogenic food. It is the most important public health problem in developing countries like Ethiopia. Endemic iodine deficiency and autoimmune disease remain a major cause of hypothyroidism. Iodine deficiency during pregnancy increases the risk of spontaneous abortion, stillbirth, reduced intelligence, neurological cretinism, poor cognitive functions, and delayed psychomotor developments