ABSTRACT Background: Intestinal parasitic infections are widely distributed all over the world and comprise great health concerns in resource poor countries. Up to 600 million school children are living in area where high transmission of intestinal parasitic infections are common. Moreover malnutrition is responsible for the death of 7.6 million children in the globe every year. Even though conclusive results have been not yet obtained, several studies showed various factors for intestinal parasitosis and malnutrition. Objective: This study aims to assess the magnitude of intestinal parasitic infections, malnutrition and associated factors among students at Zenzelima primary school. Methods: A school based cross-sectional study was conducted from January to May 2018. A total of 405 school children were selected by using systematic random sampling. Fresh stool samples were processed by direct wet mount microscopy and formol-ether concentration technique. Z-scores of children’s anthropometric statuses were generated using the WHOAnthroPlus software. A structured questionnaire was used to collect socio-demographic variables and associated factors for intestinal parasitic infection and malnutrition. EpiData statistical software version 3.1 and SPSS statistical software version 23 were used for cleanup and analysis. Descriptive statistics, chi-square test and logistic regression analysis was done. P-value less than 0.05 at 95% CI was used to declare statistical significance Results: The overall prevalence of intestinal parasitic infection in this study was 201(49.6%). The highest prevalence was due to hookworm infection 108(26.7%). In multivariate analysis, school children who never wore protective shoes were at higher odds of intestinal parasitic infections (AOR = 2.314, 95% CI: 1.285-4.167, P = 0.005). In anthropometric measurements, the current study identified 59(14.6%) underweight, 105(25.9%) stunting and 199(49.1%) thinness. The prevalence of intestinal parasitic infections, among underweight, stunted and thin school children was 59(67.8%), 57(54.3 %) and 108(54.3 %), respectively. In multiple logistic regression analysis children with illiterate mother were significantly thinner (AOR = 1.806, 95% CI = 1.146-2.845). Conclusions: Intestinal parasitosis and malnutrition were high in the study area. Lack of protective shoe wearing was significantly associated with intestinal parasitic infections and mothers’ educational status was a predictor of thinness of the school children. The community leaders should advocate the habit of protective shoes for children and improving educational status for school children parents. Key words: Intestinal parasitosis, Malnutrition,