The negative impact of water hyacinth (Eichhornia crassipes) is the current sever problem in Ethiopia particularly in Lake Tana. In this study, an experiment on the utilization of water hyacinth biomass into vermin-tea as a management tool to control the weed in Lake Tana on was conducted in Sheha-Gomenege Kebele, in Gondar Zuriya District using tomato plant. The objective of this research was to design the production of vermin-tea from water hyacinth (Eichhornia crassipes) and utilizing of vermin-tea as a nutrient amendment in open filed tomato production system as an alternative means to eradicate the invasive weed from Lake Tana. Randomized completely block design with three replications and eight treatments with vermin-tea at different concentrations, inorganic fertilizer and control group were used under field conditions. Thus, the field treatments design includes the control group(T1), the recommended dose fertilizer (T2), and different concentration levels of vermin-tea ((drenching system at 5%(T3), 10%(T4) and 15%(T5)) and also foliar application at 5%(T6), 10%(T7) and 15% (T8) with three replications for each treatment. The tomato seedlings were transplanted after 20 days of sowing. The evaluations were done based on various morphological parameters of tomato plant (plant height, leaf area, primary branches per plant, stem diameter, fruit diameter, number of fruits per plant) and the quality analysis of the fruit product. Significant differences related to tomato plant morphology were observed on vermin-tea and chemical fertilizer application treatments. In morphology (84.06cm, 75.81cm, 60.25cm, 56.34cm mean plant height), (1435.38 mm2, 1375.18 mm2,1010.33 mm2, 598.50 mm2 mean leaf area), (7.56cm ,5.92cm,7.40cm,5.67cm mean stem diameter), (6.00,5.42,4.17 ,3.50 mean primary branches per plant) were recorded on 15% foliar system vermin-tea, 15% drenching form of vermin-tea, chemical fertilizer and the control group respectively. Mean number of tomato fruits per plant (27.42, 23.04, 14.50, and 9.25) were recorded at 10% foliar form of vermin-tea, 15%drenching, chemical fertilizers and on the control group respectively. The mean weight of tomato fruit (152.79±50.97g, 145.21±44.12g, 91.44±43.36736,79.18±43.14g) were recorded at 10% foliar form of vermin tea, 5% foliar form of vermin tea, chemical fertilizer and the control group respectively. The highest value of vitamin _ ‘C’_ and lycopene contents of tomato fruit juice was recorded on 15% vermin-tea foliar form application. There was mean difference in PH value and electrical conductivity of soil between tomato plants before planting and after harvesting. Based on the results of this study, it is possible to conclude that as vermin-tea can enhance most of the growth and yield attributes of tomato. In addition, the process of vermicomposting and using vermin-tea as organic fertilizer is the most effective method for utilization and management to control the weed of bad weeds such as water hyacinth.