Teff (Eragrostis tef) is an indigenous crop plant in Ethiopia, where it was originated. It provides the most staple food Injera for most Ethiopians. The aim of this study was to determine the concentration of seven essential metals (Mg, Fe, Ni, Mn, Cu, Zn and Cr) and two non-essential metals (Pb and Cd) in red teff samples collected from three different sites (Aroriya, Anfargie and Nekosa) of Simada Woreda. A 0.5 g of oven dried samples were wet digested using 3 ml HNO3 (65-70 %) and 2 ml H2O2 (30 %) for 2:30 hours at the temperature of 120 ° C and determination was made by ICP-OES. The method was validated by excellent recovery result in the range of 89-105%. Excel and SPSS software was used to calculate and compare the mean concentration of metals. The average concentration of metals in all studied sites expressed in mg/kg dry weight of teff were Mg (1747±4.48), Cr (84±0.52), Fe (518±2.56), Mn (108±0.83), Ni (52±0.34), Cu (5.5±0.05), Zn (37±0.09), Cd (0.9±0.01) and Pb (1.9±0.04). Among the studied metals, Mg was found to be of the highest level of concentration in all red teff sampling sites. Analysis of variance indicates that no significant difference between the mean concentrations of Fe, Mn and Pb among the Aroriya and Nekosa teff samples, but there was a significant difference for the other studied metals among the corresponding red teff samples at 95% confidence level. The results indicated that teff grain is a good source of essential nutrients compared to wheat, sorghum, barley, maize, and rice which are alternatively used in Ethiopia