The study was conducted in Karita Wuha watershed (Atlaku and Menu Catchments) in West Belesa Woreda the uplands of Tekeze River Basin, Ethiopia. My study presents Runoff and sediment Yield determination for Menu and Atlaku catchments. During the rainy period of 2019 and 2020 Precipitation were measured continuously in both catchments using both manual and automatic rain wise rain gauge instruments. The river cross section was surveyed using leveling instrument and the velocity was determined by floating method, the surface velocity were multiplied by two-third for calculating mean velocity to compute the mean discharge. The discharge were determined by velocity area method, the area obtained by area staff gauge model and the velocity was the average velocity obtained from two third of surface velocity then the best fit stage discharge rating curve was developed from all the 20- minute flow depths. A 0.6 liter of water was sampled using bottles and taken to be filtrated using Whitman filter paper to compute the mass of suspended sediment concentration and sediment rating curves were also develop. The annual runoff depth varies between 191.08mm and 124.99mm with an average of 158.03mm for Atlaku catchment and between 125.08mm and 73.96mmwith an average of 99.52mm for Menu catchment. The annual Sediment yield for Atlaku catchment was decreased from 36.47ton/ha/yr in 2019 to 28.43ton/ha/yr in 2020and the annual Sediment yield for Menu catchment are decreased from 27.4ton/ha/yr in 2019 to 21.13ton/ha/yr in 2020 following installation of soil water conservation practice in 2020 but the watershed still categorized in high class of erosion and needs farther conservation practice.